{
    "id": 418,
    "date": "2016-12-28T16:19:00",
    "date_gmt": "2016-12-28T16:19:00",
    "guid": {
        "rendered": "http:\/\/new.vet.uth.gr\/?page_id=418"
    },
    "modified": "2026-03-10T13:11:16",
    "modified_gmt": "2026-03-10T11:11:16",
    "slug": "ergastirio-farmakologias-toxikologias",
    "status": "publish",
    "type": "page",
    "link": "https:\/\/www.vet.uth.gr\/en\/?page_id=418",
    "title": {
        "rendered": "Department of Pharmacology and Toxicology"
    },
    "content": {
        "rendered": "<p>[et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_fullwidth_image src=&#8221;http:\/\/www.vet.uth.gr\/wp-content\/uploads\/2020\/01\/farmakologia.png&#8221; _builder_version=&#8221;4.16&#8243; animation_style=&#8221;slide&#8221; animation_direction=&#8221;left&#8221; animation_duration=&#8221;500ms&#8221; animation_intensity_slide=&#8221;10%&#8221; animation=&#8221;left&#8221; border_style=&#8221;solid&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_fullwidth_image][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3><strong>Laboratory of Pharmacology and Toxicology<\/strong><\/h3>\n<p>&nbsp;<\/p>\n<p><strong>Discipline:<\/strong><\/p>\n<p>Research on mechanisms of drug action, drug interaction, drug action in animals as well as toxicology of drugs, toxic substances and plants in animals.<\/p>\n<div class=\"et_pb_module et_pb_text et_pb_text_0 et_pb_text_align_left et_pb_bg_layout_light\">\n<div class=\"et_pb_text_inner\">\n<p><strong>Research interests:<\/strong><\/p>\n<ol>\n<li>Design and development of new anticancer agents.<\/li>\n<li>Study of molecular mechanisms of action of anticancer drugs and chemical inducers of differentiation of neoplastic cells.<\/li>\n<li>Relationship of cell proliferation, differentiation and apoptosis and their role of gene expression in these processes.<\/li>\n<li>Structure, function and genetic basis of metabolism of drugs via cytochrome P450 in food producing and companion animals.<\/li>\n<li>Molecular basis of metabolism of xenobiotics (drugs, toxic compounds) and endogenous compounds in animals and the genetic basis of the differences observed in metabolism of xenobiotics in animals.<\/li>\n<li>Study of antibiotic resistance.<\/li>\n<li>Pharmacokinetic of veterinary drugs.<\/li>\n<li>Neurodegenerative diseases and potent targets.<\/li>\n<li>Evaluation of potency and safety of drugs and vaccines.<\/li>\n<li>Role of neurotransmitters and their receptors, developmental and neurotrophic factors in cell growth and fate of neural precursor cells of the central nervous system.<\/li>\n<li>Mechanism of control of cell growth, differentiation and survival of stem cells.<\/li>\n<li>Development of new methods of mRNA transfer in cells and application of this technology in clinical practice.<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<p><strong>Patents: <\/strong><\/p>\n<p class=\"translation-block\">Method for the development of a delivery platform to produce deliverable PTD-IVT-mRNA therapeutics, REF: GR-9389, Application number 20190100504 (11-11-2019). Hellenic Industrial Property Organization<\/p>\n<p><strong>Project in progress:\u00a0<\/strong><\/p>\n<p>Development of innovative approach of CAR (Chimeric antigen receptors) technology in the context of oral cancer immunotherapy (2020-2022)<\/p>\n<p>&nbsp;<\/p>\n<div class=\"et_pb_module et_pb_text et_pb_text_0 et_pb_text_align_left et_pb_bg_layout_light\">\n<div class=\"et_pb_text_inner\">\n<p><em>To view the Curriculum Vitae or Personal Webpage of each member of the Department, click on the corresponding link.<\/em><\/p>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][et_pb_divider show_divider=&#8221;off&#8221; disabled_on=&#8221;on|on|off&#8221; _builder_version=&#8221;4.16&#8243; height=&#8221;2px&#8221; hide_on_mobile=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_text _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; use_border_color=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3><strong>Clinic Director<\/strong><\/h3>\n<p>[\/et_pb_text][et_pb_team_member name=&#8221;\u0399\u03c9\u03ac\u03bd\u03bd\u03b7\u03c2 \u03a0\u03b1\u03c0\u03c0\u03ac\u03c2&#8221; position=&#8221;\u0391\u03bd\u03b1\u03c0\u03bb\u03b7\u03c1\u03c9\u03c4\u03ae\u03c2 \u039a\u03b1\u03b8\u03b7\u03b3\u03b7\u03c4\u03ae\u03c2&#8221; image_url=&#8221;http:\/\/www.vet.uth.gr\/wp-content\/uploads\/2020\/01\/Pappas-e1577981066235.jpg&#8221; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><a href=\"https:\/\/www.vet.uth.gr\/en\/?project=%cf%80%ce%b1%cf%80%cf%80%ce%ac%cf%82-%ce%b9%cf%89%ce%ac%ce%bd%ce%bd%ce%b7%cf%82\">Personal Webpage<\/a><\/p>\n<p>[\/et_pb_team_member][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3><b>Staff<\/b><\/h3>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_team_member name=&#8221;\u03a3\u03bf\u03c6\u03af\u03b1 \u0393\u03b5\u03c9\u03c1\u03b3\u03af\u03bf\u03c5&#8221; position=&#8221;\u039c\u03b5\u03c4\u03b1\u03b4\u03b9\u03b4\u03b1\u03ba\u03c4\u03bf\u03c1\u03b9\u03ba\u03ae \u0395\u03c1\u03b5\u03c5\u03bd\u03ae\u03c4\u03c1\u03b9\u03b1&#8221; image_url=&#8221;https:\/\/www.vet.uth.gr\/wp-content\/uploads\/2020\/12\/Georgiou-Sofia.jpg&#8221; _builder_version=&#8221;4.16&#8243; border_style=&#8221;solid&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><a href=\"https:\/\/www.vet.uth.gr\/wp-content\/uploads\/2020\/12\/Georgiou-Sofia-CV-EN.pdf\">Full curriculum Vitae<\/a><\/p>\n<p>[\/et_pb_team_member][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_team_member name=&#8221;\u0399\u03ac\u03c3\u03c9\u03bd-\u03a3\u03c0\u03c5\u03c1\u03af\u03b4\u03c9\u03bd \u03a0\u03b1\u03c4\u03b5\u03c1\u03b3\u03b9\u03b1\u03bd\u03bd\u03b1\u0384\u03ba\u03b7\u03c2&#8221; image_url=&#8221;https:\/\/www.vet.uth.gr\/wp-content\/uploads\/2026\/03\/Photo_Patergiannakis.png&#8221; position=&#8221;\u03a5\u03c0\u03bf\u03c6\u03ae\u03c8\u03b9\u03bf\u03c2 \u0394\u03b9\u03b4\u03ac\u03ba\u03c4\u03c9\u03c1&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; title_text=&#8221;Photo_Patergiannakis&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;][\/et_pb_team_member][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>",
        "protected": false
    },
    "excerpt": {
        "rendered": "<p>\u0395\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03a6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03a4\u03bf\u03be\u03b9\u03ba\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 &nbsp; \u0391\u03bd\u03c4\u03b9\u03ba\u03b5\u03af\u00b5\u03b5\u03bd\u03bf: \u0397 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03c4\u03c9\u03bd \u00b5\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u00b5\u03ce\u03bd \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2 \u03c4\u03c9\u03bd \u03c6\u03b1\u03c1\u00b5\u03ac\u03ba\u03c9\u03bd, \u03c4\u03c9\u03bd \u03b1\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03ce\u03bd \u03c4\u03bf\u03c5\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03c3\u03c4\u03b1 \u03b6\u03ce\u03b1, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03c9\u03bd \u03c4\u03c9\u03bd \u03c4\u03bf\u03be\u03b9\u03ba\u03ce\u03bd \u03bf\u03c5\u03c3\u03b9\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03c6\u03c5\u03c4\u03ce\u03bd \u03ba\u03c4\u03b7\u03bd\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03bf\u03cd \u03b5\u03bd\u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd\u03c4\u03bf\u03c2 \u03c3\u03c4\u03b1 \u03b6\u03ce\u03b1. \u0395\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03b5\u03bd\u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd\u03c4\u03b1: \u03a3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03cc\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03bd\u03ad\u03c9\u03bd \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03b9\u03ba\u03ce\u03bd \u03b5\u03bd\u03ce\u03c3\u03b5\u03c9\u03bd. \u039c\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c4\u03c9\u03bd \u03bc\u03bf\u03c1\u03b9\u03b1\u03ba\u03ce\u03bd \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03ce\u03bd \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2 \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03b9\u03ba\u03ce\u03bd \u03b5\u03bd\u03ce\u03c3\u03b5\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c7\u03b7\u03bc\u03b9\u03ba\u03ce\u03bd \u03b5\u03c0\u03b1\u03b3\u03c9\u03b3\u03ad\u03c9\u03bd \u03c4\u03b7\u03c2 [&hellip;]<\/p>",
        "protected": false
    },
    "author": 1,
    "featured_media": 879,
    "parent": 0,
    "menu_order": 0,
    "comment_status": "closed",
    "ping_status": "closed",
    "template": "",
    "meta": {
        "_et_pb_use_builder": "on",
        "_et_pb_old_content": "",
        "_et_gb_content_width": "",
        "footnotes": ""
    },
    "class_list": [
        "post-418",
        "page",
        "type-page",
        "status-publish",
        "has-post-thumbnail",
        "hentry"
    ],
    "_links": {
        "self": [
            {
                "href": "https:\/\/www.vet.uth.gr\/en\/index.php?rest_route=\/wp\/v2\/pages\/418",
                "targetHints": {
                    "allow": [
                        "GET"
                    ]
                }
            }
        ],
        "collection": [
            {
                "href": "https:\/\/www.vet.uth.gr\/en\/index.php?rest_route=\/wp\/v2\/pages"
            }
        ],
        "about": [
            {
                "href": "https:\/\/www.vet.uth.gr\/en\/index.php?rest_route=\/wp\/v2\/types\/page"
            }
        ],
        "author": [
            {
                "embeddable": true,
                "href": "https:\/\/www.vet.uth.gr\/en\/index.php?rest_route=\/wp\/v2\/users\/1"
            }
        ],
        "replies": [
            {
                "embeddable": true,
                "href": "https:\/\/www.vet.uth.gr\/en\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=418"
            }
        ],
        "version-history": [
            {
                "count": 34,
                "href": "https:\/\/www.vet.uth.gr\/en\/index.php?rest_route=\/wp\/v2\/pages\/418\/revisions"
            }
        ],
        "predecessor-version": [
            {
                "id": 12394,
                "href": "https:\/\/www.vet.uth.gr\/en\/index.php?rest_route=\/wp\/v2\/pages\/418\/revisions\/12394"
            }
        ],
        "wp:featuredmedia": [
            {
                "embeddable": true,
                "href": "https:\/\/www.vet.uth.gr\/en\/index.php?rest_route=\/wp\/v2\/media\/879"
            }
        ],
        "wp:attachment": [
            {
                "href": "https:\/\/www.vet.uth.gr\/en\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=418"
            }
        ],
        "curies": [
            {
                "name": "wp",
                "href": "https:\/\/api.w.org\/{rel}",
                "templated": true
            }
        ]
    }
}